Medical Knowledge Cockpit candidiasis, familial

• egf signaling pathway
  species not specified one gene

  ---

• mapkinase signaling pathway
  species not specified one gene

  ---

• ifn alpha signaling pathway
  species not specified one gene

  ---

TRAF3IP2

• Act1, an NF-kappa B-activating protein

CARD9

• Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
• A homozygous CARD9 mutation in a family with susceptibility to fungal infections

CLEC7A

• The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment
• The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages
• CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells

IL17RA

• Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression
• Molecular characterization of the human interleukin (IL)-17 receptor

STAT1

• Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription
• The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors
• Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport
• The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality
• The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex