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epilepsy, focal, with speech disorder and with or without mental retardation
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Cancer Gene Census
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GRIN2A
Somatic tumors
melanoma, colorectal carcinoma, gastric carcinoma, lung carcinoma
Tumor types germline
Cancer Syndrom
Translocation partner
Name
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Chromosome banding
16p13.2
Cancer molecular gen.
Rec
Mutation type
Mis, N, F, O
Other syndrome disease
Focal epilepsy and speech disorder with or without mental retardation
Definition
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PubMed Links
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GRIN2A
NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A(NR2A) and interaction of Pyk2 and Src with NR2A after transient cerebral ischemia and reperfusion
Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death
HIV tat and neurotoxicity
Heteromeric NMDA receptors: molecular and functional distinction of subtypes
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
Pathways
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Clinical Trials
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