Medical Knowledge Cockpit hemangioblastoma, cerebellar, somatic

VHL

• A novel mutation in the von Hippel������Lindau tumor suppressor gene identified in a Japanese family with pheochromocytoma and hepatic hemangioma
• Von Hippel������Lindau Syndrome
• von Hippel������Lindau tumor suppressor: not only HIF's executioner
• Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
• The von Hippel������Lindau tumor suppressor protein and clear cell renal carcinoma

VHL

Somatic tumors

renal, haemangioma, pheochromocytoma

Tumor types germline

renal, haemangioma, pheochromocytoma

Cancer Syndrom

Von Hippel-Lindau syndrome

Translocation partner

Name

von Hippel-Lindau syndrome gene

Chromosome banding

3p25

Cancer molecular gen.

Rec

Mutation type

D, Mis, N, F, S

Other syndrome disease