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leukemia, acute lymphoblastic, susceptibility to
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PAX5
Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9
Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma
The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene
HOXD4
Complete mutation analysis panel of the 39 human HOX genes
Mutation analysis of the HOX paralogous 4-13 genes in children with acute lymphoid malignancies: identification of a novel germline mutation of HOXD4 leading to a partial loss-of-function
Cancer Gene Census
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PAX5
Somatic tumors
NHL, ALL, B-ALL
Tumor types germline
Cancer Syndrom
Translocation partner
IGH, ETV6, PML, FOXP1, ZNF521, ELN
Name
paired box gene 5 (B-cell lineage specific activator protein)
Chromosome banding
9p13
Cancer molecular gen.
Dom
Mutation type
T, Mis, D, F, S
Other syndrome disease
Definition
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Pathways
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Clinical Trials
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