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optic nerve hypoplasia
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Phagosome
Homo sapiens (human)
one gene
Clinical Trials
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Cancer Gene Census
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SOX2
Somatic tumors
NSCLC, oesophageal squamous carcinoma
Tumor types germline
Cancer Syndrom
Translocation partner
Name
SRY (sex determining region Y)-box 2
Chromosome banding
3q26.3-q27
Cancer molecular gen.
Dom
Mutation type
A
Other syndrome disease
Microphthalmia and oesophageal atresia syndrome
PubMed Links
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SOX2
Thyroid hormone signaling acts as a neurogenic switch by repressing Sox2 in the adult neural stem cell niche
Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene
Regulation of the pluripotency marker Rex-1 by Nanog and Sox2
Pairing SOX off: with partners in the regulation of embryonic development
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families
PAX6
The human PAX6 gene is mutated in two patients with aniridia
TUBA8
TUBA8: A new tissue-specific isoform of alpha-tubulin that is highly conserved in human and mouse
Definition
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