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piebaldism
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Pathways
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Pathways in cancer
Homo sapiens (human)
one gene
Definition
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Cancer Gene Census
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KIT
Somatic tumors
GIST, AML, TGCT, mastocytosis, mucosal melanoma
Tumor types germline
GIST, epithelioma
Cancer Syndrom
familial gastrointestinal stromal tumour
Translocation partner
Name
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Chromosome banding
4q12
Cancer molecular gen.
Dom
Mutation type
Mis, O
Other syndrome disease
Piebald trait
Clinical Trials
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PubMed Links
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KIT
Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes
Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand
Generation of a prostate from a single adult stem cell
c-Kit--a hematopoietic cell essential receptor tyrosine kinase
SNAI2
Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells
The transcriptional repressor Snail promotes mammary tumor recurrence
Androgen regulation of prostasin gene expression is mediated by sterol-regulatory element-binding proteins and SLUG