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Pathways     No results

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  • Pancreatic cancer
    Homo sapiens (human) 3 genes
  • Pathways in cancer
    Homo sapiens (human) 3 genes
  • Bladder cancer
    Homo sapiens (human) 3 genes
  • Glioma
    Homo sapiens (human) 2 genes
  • Melanoma
    Homo sapiens (human) 2 genes
  • Hepatitis C
    Homo sapiens (human) 2 genes
Clinical Trials     No results

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Cancer Gene Census     No results

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ERBB2

Somatic tumors
breast, ovarian, other tumour types, NSCLC, gastric
Tumor types germline
Cancer Syndrom
Translocation partner
Name
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Chromosome banding
17q21.1
Cancer molecular gen.
Dom
Mutation type
A, Mis, O
Other syndrome disease
Definition     No results

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ASCC1

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is atranscriptional coactivator that plays an important role in gene transactivation by multiple transcriptionfactors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF).The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivationby the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. (provided byRefSeq, Dec 2011)

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex

The ASC-1 complex is atranscriptional coactivator that plays an important role in gene transactivation by multiple transcriptionfactors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF).The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivationby the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. (provided byRefSeq, Dec 2011)

PubMed Links     No results

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EGFR