Add Custom Markers
Pathways     No results

An error occurred

  • Cleavage of the damaged purine
    species not specified one gene
Clinical Trials     No results

An error occurred

Cancer Gene Census     No results

An error occurred

PLAG1

Somatic tumors
salivary adenoma, lipoblastoma
Tumor types germline
Cancer Syndrom
Translocation partner
TCEA1, LIFR, CTNNB1, CHCHD7, COL1A2, HAS2
Name
pleiomorphic adenoma gene 1
Chromosome banding
8q12
Cancer molecular gen.
Dom
Mutation type
T
Other syndrome disease
PubMed Links     No results

An error occurred

Definition     No results

An error occurred

MUTYH

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases fromthe DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus andmitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multipletranscript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair

The enzyme excises adenine bases fromthe DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus andmitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multipletranscript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)