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ADH1B
Genetics of human alcohol and aldehyde dehydrogenases
ADH1C
Three-dimensional structures of the three human class I alcohol dehydrogenases
A proline-threonine substitution in codon 351 of ADH1C is common in Native Americans
GABRA2
Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors
gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties
HTR2A
9-(Aminomethyl)-9,10-dihydroanthracene is a novel and unlikely 5-HT<sub>2A</sub> receptor antagonist
Application of ligand SAR, receptor modeling and receptor mutagenesis to the discovery and development of a new class of 5-HT<sub>2A</sub> ligands
Spiro[9,10-dihydroanthracene]-9,3'-pyrrolidine-a structurally unique tetracyclic 5-HT<sub>2A</sub> receptor antagonist
Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT<sub>2A</sub> receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation
2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT<sub>2A</sub> ligands
5-hydroxytryptamine2A receptor inverse agonists as antipsychotics
Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist
RCBTB1
Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia
TAS2R16
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
Members of RTP and REEP gene families influence functional bitter taste receptor expression.
Cancer Gene Census
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Taste transduction
Homo sapiens (human)
one gene
Clinical Trials
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Definition
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