Medical Knowledge Cockpit anorexia nervosa, susceptibility to

HTR2A

• Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment
• Genetic markers of suicidal ideation emerging during citalopram treatment of major depression
• The pharmacogenetics of major depression: past, present, and future
• Decreased hippocampal 5-HT_2A receptor binding in major depressive disorder: in vivo measurement with [¹⁸F]-altanserin positron emission tomography
• Cerebral 5-HT_2A receptor binding is increased in patients with Tourette's syndrome

• Visualisation of loss of 5-HT_2A receptors with age in healthy volunteers using [¹⁸F]-altanserin and positron emission tomographic imaging
• Primary structure of the human platelet serotonin 5-HT₂ receptor: identity with frontal cortex serotonin 5-HT_2A receptor
• The human polyomavirus, JCV, uses serotonin receptors to infect cells

BDNF

• Neurotrophin receptors TrkB.T1 and p75NTR cooperate in modulating both functional and structural plasticity in mature hippocampal neurons
• NMDA-mediated and self-induced bdnf exon IV transcriptions are differentially regulated in cultured cortical neurons
• Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment
• Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism
• BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability

• A physiological role for the dopamine D5 receptor as a regulator of BDNF and Akt signalling in rodent prefrontal cortex
• The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
• Variant BDNF (Val66Met) impact on brain structure and function
• Toward a unified biological hypothesis for the BDNF Val66Met-associated memory deficits in humans: a model of impaired dendritic mRNA trafficking
• A simple role for BDNF in learning and memory?
• The Role of BDNF in the Development of Fear Learning
• BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

• role of erk5 in neuronal survival pathway
  species not specified one gene

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