Medical Knowledge Cockpit brachiootic syndrome

SIX1

Somatic tumors

Wilms tumour

Tumor types germline

Cancer Syndrom

Translocation partner

Name

SIX homeobox 1

Chromosome banding

14q23.1

Cancer molecular gen.

Mutation type

Mis

Other syndrome disease

SIX1

• Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein
• Six3 and Six6 activity is modulated by members of the groucho family