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cerebellar ataxia, deafness
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DNMT1
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA
Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
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