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cutaneous telangiectasia and cancer syndrome, familial
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Cancer Gene Census
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ATR
Somatic tumors
endometrial, gastric, epithelial ovarian, myeloma
Tumor types germline
oropharyngeal
Cancer Syndrom
familial cutaneous telangiectasia and cancer syndrome
Translocation partner
Name
ATR serine/threonine kinase
Chromosome banding
3q23
Cancer molecular gen.
Dom
Mutation type
F; Mis
Other syndrome disease
Seckel syndrome 1
Definition
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Pathways
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PubMed Links
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ATR
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
Clinical Trials
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