Medical Knowledge Cockpit diabetes, type 1

• Progesterone-mediated oocyte maturation
  Homo sapiens (human) one gene

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• GnRH signaling pathway
  Homo sapiens (human) one gene

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• Insulin signaling pathway
  Homo sapiens (human) one gene

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INS

• Insulin: understanding its action in health and disease
• A reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex
• What's fueling the biotech engine-2011 to 2012
• Insulin-related material in microbes: similarities and differences from mammalian insulins
• A review of piscine islet xenotransplantation using wild-type tilapia donors and the production of transgenic tilapia expressing a "humanized" tilapia insulin

• Specialized insulin is used for chemical warfare by fish-hunting cone snails
• Sequence of the human insulin gene
• Regulation of insulin gene transcription

BLK

• Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk)

OAS1

• A sequence-ready physical map of a region of 12q24.1

ITPR3

• Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors

PTPN22

• Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
• Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect
• Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes