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diabetes mellitus, type i
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AKT2
pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167.
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.
Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2.
FOXP3
A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells
Mutational analysis of the FOXP3 gene and evidence for genetic heterogeneity in the immunodysregulation, polyendocrinopathy, enteropathy syndrome
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
Control of regulatory T cell development by the transcription factor Foxp3
Cancer Gene Census
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AKT2
Somatic tumors
ovarian, pancreatic
Tumor types germline
Cancer Syndrom
Translocation partner
Name
v-akt murine thymoma viral oncogene homolog 2
Chromosome banding
19q13.1-q13.2
Cancer molecular gen.
Dom
Mutation type
A
Other syndrome disease
Definition
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Pathways
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Epstein-Barr virus infection
Homo sapiens (human)
one gene
Pathways in cancer
Homo sapiens (human)
one gene
Colorectal cancer
Homo sapiens (human)
one gene
Pancreatic cancer
Homo sapiens (human)
one gene
Endometrial cancer
Homo sapiens (human)
one gene
Clinical Trials
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