Medical Knowledge Cockpit encephalopathy, acute

• Pertussis
  Homo sapiens (human) one gene

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RANBP2

Somatic tumors

inflammatory myofibroblastic tumour

Tumor types germline

Cancer Syndrom

Translocation partner

ALK

Name

RAN binding protein 2

Chromosome banding

2q12.3

Cancer molecular gen.

Dom

Mutation type

T

Other syndrome disease

RANBP2

• The Ran/TC4 GTPase-binding domain: identification by expression cloning and characterization of a conserved sequence motif
• Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region
• Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1
• Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin

CPT2

• Identification of 5' regulatory regions of the human carnitine palmitoyltransferase II gene
• Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides
• Identification of a common mutation in the carnitine palmitoyltransferase II gene in familial recurrent myoglobinuria patients