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endometrial cancer, familial
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Clinical Trials
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External
Study of Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer
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MSH6
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
Molecular cloning of the N-terminus of GTBP
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
Definition
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Cancer Gene Census
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MSH6
Somatic tumors
colorectal
Tumor types germline
colorectal, endometrial, ovarian
Cancer Syndrom
hereditary non-polyposis colorectal cancer
Translocation partner
Name
mutS homolog 6 (E. coli)
Chromosome banding
2p16
Cancer molecular gen.
Rec
Mutation type
Mis, N, F, S
Other syndrome disease