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episodic pain syndrome, familial
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SCN10A
Prostaglandin E2 promotes Na1.8 trafficking via its intracellular RRR motif through the protein kinase A pathway
PKC���� phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice
Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome
NGF as a mediator of inflammatory pain
SCN11A
A de novo gain-of-function mutation in SCN11A causes loss of pain perception
TRPA1
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents
Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor
Nicotine activates the chemosensory cation channel TRPA1
Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel
TRPA1: the central molecule for chemical sensing in pain pathway?
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External
Painful Channelopathies Study (PCS)