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RAD51C

This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA andSaccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA.This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junctionresolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of fourlocalized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpressionof the four genes during amplification has been observed and suggests a possible role in tumor progression.Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jul 2013)

This gene is a member of the RAD51 family

RAD51 family members are highly similar to bacterial RecA andSaccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA.This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junctionresolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of fourlocalized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpressionof the four genes during amplification has been observed and suggests a possible role in tumor progression.Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jul 2013)

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