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TSHR

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. Theencoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylatecyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Dec 2008)

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism

Theencoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylatecyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Dec 2008)

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TSHR

Somatic tumors
toxic thyroid adenoma
Tumor types germline
thyroid adenoma
Cancer Syndrom
Translocation partner
Name
thyroid stimulating hormone receptor
Chromosome banding
14q31
Cancer molecular gen.
Dom
Mutation type
Mis
Other syndrome disease
Hereditary nonautoimmune hyperthyroidism; subclinical hypothyroidism
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