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immunodeficiency with hyper-igm
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NF-kappa B signaling pathway
Homo sapiens (human)
one gene
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AICDA
Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
Internal IgH class switch region deletions are position-independent and enhanced by AID expression
CD40
A novel RING finger protein interacts with the cytoplasmic domain of CD40
Molecular basis for CD40 signaling mediated by TRAF3
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases