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leukemia, acute lymphocytic
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Chronic myeloid leukemia
Homo sapiens (human)
one gene
Cancer Gene Census
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TAL1
Somatic tumors
lymphoblastic leukaemia/biphasic
Tumor types germline
Cancer Syndrom
Translocation partner
TRD, STIL
Name
T-cell acute lymphocytic leukemia 1 (SCL)
Chromosome banding
1p32
Cancer molecular gen.
Dom
Mutation type
T
Other syndrome disease
PubMed Links
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BCR
Regulation of dendritic arborization by BCR Rac1 GTPase-activating protein, a substrate of PTPRT
The BCR-ABL oncoprotein potentially interacts with the xeroderma pigmentosum group B protein
e19a2-positive chronic myeloid leukaemia with BCR exon e16-deleted transcripts
TAL1
Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells
SCL and related hemopoietic helix-loop-helix transcription factors.
Involvement of the putative hematopoietic transcription factor SCL in T-cell acute lymphoblastic leukemia.
Definition
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Clinical Trials
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External
Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO) (CARPASCIO)
CD19 CAR T Cells in Patients With Resistant or Refractory CD19+ Acute Lymphoblastic Leukemia
Study of Clofarabine, Etoposide, Cyclophosphamide [CEC], Liposomal Vincristine (VCR), Dexamethasone and Bortezomib in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LL)
A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible Patients
IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCT