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male germ cell tumor
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Cancer Gene Census
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BCL10
Somatic tumors
MALT
Tumor types germline
Cancer Syndrom
Translocation partner
IGH
Name
B-cell CLL/lymphoma 10
Chromosome banding
1p22
Cancer molecular gen.
Dom
Mutation type
T
Other syndrome disease
Definition
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PubMed Links
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BCL10
Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes
NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein
Pathways
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T cell receptor signaling pathway
Homo sapiens (human)
one gene
Clinical Trials
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