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mast cell disease
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Cancer Gene Census
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KIT
Somatic tumors
GIST, AML, TGCT, mastocytosis, mucosal melanoma
Tumor types germline
GIST, epithelioma
Cancer Syndrom
familial gastrointestinal stromal tumour
Translocation partner
Name
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Chromosome banding
4q12
Cancer molecular gen.
Dom
Mutation type
Mis, O
Other syndrome disease
Piebald trait
Pathways
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Definition
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PubMed Links
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KIT
Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand
Generation of a prostate from a single adult stem cell
c-Kit--a hematopoietic cell essential receptor tyrosine kinase
Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults
Clinical Trials
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External
Study of Factors Regulating Mast Cell Proliferation