Medical Knowledge Cockpit meningioma, familial, susceptibility to

SMARCE1

• SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones
• Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

SUFU

• Characterization of the physical interaction of Gli proteins with SUFU proteins

SUFU

Somatic tumors

medulloblastoma

Tumor types germline

medulloblastoma

Cancer Syndrom

medulloblastoma predisposition

Translocation partner

Name

suppressor of fused homolog (Drosophila)

Chromosome banding

10q24.32

Cancer molecular gen.

Rec

Mutation type

D, F, S

Other syndrome disease