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meningioma, nf2-related, somatic
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NF2
VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation
Homotypic and heterotypic interaction of the neurofibromatosis 2 tumor suppressor protein merlin and the ERM protein ezrin
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NF2
Somatic tumors
meningioma, acoustic neuroma, renal
Tumor types germline
meningioma, acoustic neuroma
Cancer Syndrom
neurofibromatosis type 2
Translocation partner
Name
neurofibromatosis type 2 gene
Chromosome banding
22q12.2
Cancer molecular gen.
Rec
Mutation type
D, Mis, N, F, S, O
Other syndrome disease
Clinical Trials
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External
Pembrolizumab, Ixazomib Citrate, and Dexamethasone in Treating Participants With Relapsed Multiple Myeloma
Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease
Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma