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HSD17B10

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductasesuperfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fattyacids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, andmutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Severalalternatively spliced transcript variants have been identified, but the full-length nature of only two transcriptvariants has been determined. (provided by RefSeq, Jul 2008)

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductasesuperfamily

The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fattyacids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, andmutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Severalalternatively spliced transcript variants have been identified, but the full-length nature of only two transcriptvariants has been determined. (provided by RefSeq, Jul 2008)

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