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methemoglobinemia, type i
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CYB5R3
Integration of cardiac proteome biology and medicine by a specialized knowledgebase
NADH-cytochrome b5 reductase 3}}</ref> The entire gene is about 31 kb in length. Exon 2 contains the junction of the membrane-binding domain and the catalytic domain of b5R, which shows that there are two forms of b5R: a soluble form and a membrane-bound form. The 5' portion of this gene does not have typical regulatory transcriptional elements, but has the sequence G-G-G-C-G-G a total of five times. The GC content of this 5' portion of the gene is 86%, much higher than the average GC of the entire gene, which is 55%. There is also an atypical polyadenylation signal in the 3'-untranslated region of the gene.<ref>{{cite journal
Human cytochrome b5 reductase: structure, function, and potential applications
Role of cysteine residues in human NADH-cytochrome b5 reductase studied by site-directed mutagenesis. Cys-273 and Cys-283 are located close to the NADH-binding site but are not catalytically essential
CYB5A
Amino acid sequences of cytochrome b5 from human, porcine, and bovine erythrocytes and comparison with liver microsomal cytochrome b5.
Purification and properties of rat liver microsomal stearyl coenzyme A desaturase.
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