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microcephaly with or without chorioretinopathy, lymphedema
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KIF11
Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5
The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5
Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core
Disparity in allosteric interactions of monastrol with Eg5 in the presence of ADP and ATP: a difference FT-IR investigation
Loop 5-directed compounds inhibit chimeric kinesin-5 motors: implications for conserved allosteric mechanisms
Towards a quantitative understanding of mitotic spindle assembly and mechanics
The mitotic spindle: a self-made machine
The functional antagonism between Eg5 and dynein in spindle bipolarization is not compatible with a simple push-pull model
Monastrol, a prototype anti-cancer drug that inhibits a mitotic kinesin, induces rapid bursts of axonal outgrowth from cultured postmitotic neurons
Kinesin-5 regulates the growth of the axon by acting as a brake on its microtubule array
Kinesin-5 is essential for growth-cone turning
Microtubule redistribution in growth cones elicited by focal inactivation of kinesin-5
Kinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching
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