Medical Knowledge Cockpit mody, type ii

• Galactose metabolism
  Homo sapiens (human) one gene

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HNF1A

Somatic tumors

hepatic adenoma, hepatocellular

Tumor types germline

hepatic adenoma, hepatocellular carcinoma

Cancer Syndrom

familial hepatic adenoma

Translocation partner

Name

HNF1 homeobox A

Chromosome banding

12q24.2

Cancer molecular gen.

Rec

Mutation type

Mis, F

Other syndrome disease

Maturity-onset diabetes of the young, TYPE III

GCK

• Cloning and biochemical characterization of a novel mouse ADP-dependent glucokinase
• Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

HNF1A

• Interaction of a liver-specific nuclear factor with the fibrinogen and alpha 1-antitrypsin promoters