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multiple sclerosis
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Clinical Trials
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Neoadjuvant Immunotherapy With Durvalumab and Tremelimumab for Bladder Cancer Patients Ineligible for Cisplatin (NITIMIB)
Induction of Immune-mediated aBscOpal Effect thrOugh STEreotactic Radiation Therapy in Metastatic Melanoma Patients Treated by PD-1 + CTLA-4 Inhibitors
Nivolumab in Eliminating Minimal Residual Disease and Preventing Relapse in Patients With Acute Myeloid Leukemia in Remission After Chemotherapy
Pathways
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Alzheimer''s disease
Homo sapiens (human)
{:one=>"one gene", :other=>"%{count} genes"}
Toxoplasmosis
Homo sapiens (human)
3 genes
PubMed Links
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PDCD1
Activation-induced expression of human programmed death-1 gene in T-lymphocytes
The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors
Microanatomical localization of PD-1 in human tonsils
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses
Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction
Differential binding properties of B7-H1 and B7-DC to programmed death-1
HLA-DQB1
Genetic control of autoimmunity in type 1 diabetes
HLA-DRB1
Genetics of rheumatoid arthritis
TNFRSF1A
Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis
Definition
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Cancer Gene Census
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