Medical Knowledge Cockpit myelokathexis, isolated

CXCR4

• Clinical importance and therapeutic implications of the pivotal CXCL12-CXCR4 (chemokine ligand-receptor) interaction in cancer cell migration
• Tuberculosis: the changing tubercle
• Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors
• The promiscuous chemokine binding profile of the Duffy antigen/receptor for chemokines is primarily localized to sequences in the amino-terminal domain
• A proposed bovine neuropeptide Y (NPY) receptor cDNA clone, or its human homologue, confers neither NPY binding sites nor NPY responsiveness on transfected cells

CXCR4

Somatic tumors

WM

Tumor types germline

Cancer Syndrom

Translocation partner

Name

C-X-C motif chemokine receptor 4

Chromosome banding

2q21

Cancer molecular gen.

Dom

Mutation type

Mis, N, F

Other syndrome disease