Medical Knowledge Cockpit neuropathy, distal hereditary motor, type viib

DCTN1

• Interaction of huntingtin-associated protein with dynactin P150Glued
• Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells
• Human DCTN1: genomic structure and evaluation as a candidate for Alstr����m syndrome

DCTN1

Somatic tumors

inflammatory myofibroblastic tumour, Spitzoid tumour

Tumor types germline

Cancer Syndrom

Translocation partner

ALK, ROS1

Name

dynactin 1

Chromosome banding

2p13

Cancer molecular gen.

Dom

Mutation type

T

Other syndrome disease

Distal hereditary motor neuronopathy, susceptibility to amyotrophic lateral sclerosis, Perry syndrome