Medical Knowledge Cockpit peutz-jeghers syndrome

STK11

• Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

STK11

Somatic tumors

NSCLC, pancreatic

Tumor types germline

jejunal hamartoma, ovarian, testicular, pancreatic

Cancer Syndrom

Peutz-Jeghers syndrome

Translocation partner

Name

serine/threonine kinase 11 gene (LKB1)

Chromosome banding

19p13.3

Cancer molecular gen.

Rec

Mutation type

D, Mis, N, F, S

Other syndrome disease