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pheochromocytoma, susceptibility to
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Pathways
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mapkinase signaling pathway
species not specified
one gene
Definition
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Cancer Gene Census
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TMEM127
Somatic tumors
Tumor types germline
pheochromocytoma, renal cell carcinoma
Cancer Syndrom
Translocation partner
Name
transmembrane protein 127
Chromosome banding
2q11.2
Cancer molecular gen.
Rec
Mutation type
F, N
Other syndrome disease
Clinical Trials
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External
Diagnosis of Pheochromocytoma
PubMed Links
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MAX
Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity
Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors
Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor
Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc
Towards a proteome-scale map of the human protein-protein interaction network