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platelet disorder
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platelet amyloid precursor protein pathway
species not specified
one gene
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GP1BB
Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex
Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V
Genetic abnormalities of Bernard-Soulier syndrome
RUNX1
Comprehensive molecular portraits of human breast tumours
Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer
Sequence specificity of the core-binding factor
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
PLAU
Expression of the fibrinolytic components in endometriosis.
Molecular cloning of cDNA coding for human preprourokinase
Definition
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Cancer Gene Census
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RUNX1
Somatic tumors
AML, pre B-ALL, T-ALL
Tumor types germline
Cancer Syndrom
Translocation partner
RPL22, MECOM, CBFA2T3, RUNX1T1, ETV6, AFF3
Name
runt-related transcription factor 1 (AML1)
Chromosome banding
21q22.3
Cancer molecular gen.
Dom
Mutation type
T
Other syndrome disease