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sclerosteosis
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LRP4
LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome
SOST
Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins
Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation
Bone mineral density in sclerosteosis; affected individuals and gene carriers
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein
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Wnt signaling pathway
Homo sapiens (human)
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