Medical Knowledge Cockpit stuve-wiedemann syndrome/schwartz-jampel type 2 syndrome

LIFR

• The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor
• Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130
• Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors

LIFR

Somatic tumors

salivary adenoma

Tumor types germline

Cancer Syndrom

Translocation partner

PLAG1

Name

leukemia inhibitory factor receptor

Chromosome banding

5p13-p12

Cancer molecular gen.

Dom

Mutation type

T

Other syndrome disease