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PTEN
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NRAS
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasmamembrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex.The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factorand inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectalcancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenilemyelomonocytic leukemia. (provided by RefSeq, Jun 2011)This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasmamembrane
This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex.The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factorand inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectalcancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenilemyelomonocytic leukemia. (provided by RefSeq, Jun 2011)
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HRAS