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tumor predisposition syndrome
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SMARCA4
Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein
Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors
BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer
The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
BAP1
Therapeutic implications of the emerging molecular biology of uveal melanoma
Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness"
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity
Cancer Gene Census
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SMARCA4
Somatic tumors
NSCLC, SCCOHT
Tumor types germline
Cancer Syndrom
Translocation partner
Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Chromosome banding
19p13.2
Cancer molecular gen.
Rec
Mutation type
F, N, Mis, S
Other syndrome disease
Definition
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Pathways
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Clinical Trials
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External
Familial Investigations of Childhood Cancer Predisposition (SJFAMILY)