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van buchem disease
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Wnt signaling pathway
Homo sapiens (human)
2 genes
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SOST
Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice
Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
Van Buchem's disease (hyperostosis corticalis generalisata familiaris). A case report
LRP5
Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human
Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene
Functional relevance of the BMD-associated polymorphism rs312009: novel involvement of RUNX2 in LRP5 transcriptional regulation
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin
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