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weaver syndrome
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EZH2
Somatic tumors
DLBCL
Tumor types germline
Cancer Syndrom
Translocation partner
Name
enhancer of zeste homolog 2
Chromosome banding
7q35-q36
Cancer molecular gen.
Dom
Mutation type
Mis
Other syndrome disease
Pathways
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Definition
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PubMed Links
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EZH2
Normalization and subtraction: two approaches to facilitate gene discovery
Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1
Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres
Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein
Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes
Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes
Point mutations in the WD40 domain of Eed block its interaction with Ezh2
Clinical Trials
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