Tag Archives: Hasso Plattner Institute

HiGHmed Medical Informatics Consortium

Executive Summary

The HiGHmed consortium aims to develop and use innovative information infrastructures to increase the efficiency of clinical research and to swiftly translate research results into validated improvements of patient care. These aims are tightly connected with challenges to integrate and further develop solutions of innovative, internationally interoperable data integration and methods, with the aim to demonstrate their added value for health research and patient care. The concepts must be designed in a way that will help to develop sustainable structures and with the perspective for an easy roll-out to other hospitals. You might want to refer to the HiGHmed consoritum website for further details.

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    Festival of Genomics 2016 London: Real-time Exploration of the Cancer Genome, the Human Immune System (REHIS) and other NCT projects (Slides)

    The slide deck of the presentation “Real-time Exploration of the Cancer Genome, the Human Immune System (REHIS) and other NCT projects” of the workshop “Big Medical Data in Precision Medicine: Challenges or Opportunities?” on Jan 19, 2016 in London is online available now.

    Smart Analysis Health Research Access (SAHRA)

    Executive Summary

    The aim of the Smart Analysis Health Research Access (SAHRA) cooperation project is to provide scientific analysis methods incorporating latest in-memory database technology for analysis of longitudinal health data. These methods support research and the development of innovative solutions and products by providing real-time analysis of longitudinal health data for the first time. Public and governmental institutes as well as small and mid-sized healthcare enterprises are the target audience of the project. Latest data protection and privacy measures are taken to protect any data on the SAHRA platform in compliance with latest German and International data protection laws.

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    International Symposium on Big Data in Medicine

    We are happy to contribute to the Symposium “Big Data in Medicine” taking place from July 1-2, 2015 at the Hasso Plattner Institute in Potsdam, Germany. The international symposium is an interdisciplinary cooperation between the German National Academy of Sciences Leopoldina and the Hasso Plattner Institute offering a unique opportunity for science and industry experts to work on concrete issues of personalized medicine.

    Systems Medicine of Heart Failure (SMART)

    Executive Summary

    e:Med Flyer 2016The cooperation project Systems Medicine of Heart Failure (SMART) focuses on researching risk factors of heart failures. The onset and course of heart failure (HF) is triggered by a complex regulatory network that includes stressors (pressure overload by individual anatomic hemodynamic settings), intrinsic (genes), environmental (regulating epigenetics), and modifying factors (such as hormones and the immune system). SMART aims to establish individualized strategies for the prevention and management of HF by early detection of the physiological, genomic, proteomic and hemodynamic mechanisms that lead from one common cause of ventricular dysfunction (pressure overload) to maladaptive remodeling and irreversible HF. To cope with the complexity of HF, SMART will interrelate models describing the interplay between genome, proteome and cell function, regulating hormones, tissue composition and hemodynamic whole organ function up to a whole body description of a patient and patient cohorts. The ultimate goal is to demonstrate proof-of-concept tools for predicting disease evolution and efficacy of treatment in a given patient. To achieve this task SMART will apply
    – A modelling framework that couples multi-scale mechanistic models with in-depth genome/proteome, cell physiology and whole organ (biomechanical and fluid dynamic) models
    – Subsequently, investigate methods validity and relevance for “quantitative prediction” of treatment outcome in a clinical proof-of-concept trial (demonstrator) of patients with aortic valve diseases.

     

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    2014 European Life Science Award Top 3 Most Innovative New Services

    European Life Science Award 2014
    AnalyzeGenomes was honored with the European Life Science Award for the Most Innovative Service. We are happy to be select out of the variety of nominations and labeled as one of the top 3 most innovative new services in the European Life Science community of the year 2014. We received the award in connection with the ELA in Barcelona, Spain on May 13, 2014.

    HPI-Studenten liefern blitzschnell passgenaue Informationen zum Erbgut

    “Die Analyse und Auswertung riesiger Mengen genetischer Daten sind jetzt in Echtzeit möglich. Das hat ein achtköpfiges Team aus Bachelorstudenten des Hasso-Plattner-Instituts (HPI) bewiesen. Die Software der HPI-Studenten beschleunigt die Untersuchung durch Einsatz der am Institut erforschten Hauptspeicherdatenbank-Technologie, welche die Echtzeit-Analyse von Genomdaten ermöglicht. Die Projektergebnisse helfen Forschern und Ärzten, erstmals auch genetische Veränderungen bei ihren Behandlungsentscheidungen zu berücksichtigen.”

    Weiterlesen.